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April 14, 2026
Dear GenE-HumDi Members,
We are very excited to announce that GenE-HumDi (COST action CA21113) and CRISPR MEDICINE NEWS (CRISPRMED) co-organize three Workshops as part of the CRISPRMED26 Conference.
With a limited number of 30 seats per workshop, we focus on delivering high-quality, interactive workshops in which you can learn by doing instead of just listening.
The workshops will be facilitated by scientific leaders from the GenE-HumDi consortium [Open genehumdi.eu][1]who will share their knowledge and experience in a practical, case-based setting that will allow you to apply what you learn directly to your professional career.
All you need to bring is a laptop!
Register for the workshops [Open Workshop Inscription form][2].
The CRISPRMED26 workshops will take place on 14th April 2026, from 9:00 to 13:30 CEST. Each workshop will last 1 hour and 25 minutes, and the workshops will be coordinated by Karim Benabdellah and Alessia Cavazza.
Workshop Topics:
Three parallel CRISPRMED26 Workshops will be held with the following topics:
- Tools: Choosing the Right Gene-Editing Approach
- Delivery: Navigating the CRISPR Delivery Landscape
- Safety: Pre-Clinical Safety Analyses
Leading experts will coordinate each workshop with following contents:
- Tools: Choosing the Right Gene-Editing Approach
- Claudio Mussolino, (Universitaetsklinikum Freiburg. Germany)
- Raúl Perez-Jimenez, (Ikerbasque Research Professor. Spain)
- Antonio Carusillo, (Università di Modena e Reggio Emilia. Italy)
The workshop will start with an introduction to various genome-editing technologies highlighting their mechanisms, advantages, and limitations.
We will also discuss recent developments in genome-editing tools, focusing on those DSB-free and with demonstrated therapeutic potential, such as base- and prime editing. Next, we will cover criteria for selecting the appropriate genome-editing tool based on the targeted disease and present case studies of therapeutic applications.
We will emphasise that different diseases require distinct genome-editing strategies depending on the aim, such as gene replacement, gene restoration, or gene insertion.
The workshop will include a hands-on session with practical demonstrations and group activities to design genome-editing experiments. Finally, we will address ethical and safety considerations, emphasising regulatory guidelines and best practices.
The workshop will be highly interactive, with Q&A sessions throughout, pausing at key points for discussion.
- Delivery: Navigating the CRISPR Delivery Landscape
- Juan Antonio Marchal, (University of Granada.Spain)
- André Görgens, (Karolinska Institutet | Department of Laboratory Medicine, Division of Biomolecular and Cellular Medicine. Sweden)
This workshop will focus on navigating the current landscape of viral- and non-viral delivery methods for CRISPR gene-editing tools.
The session will provide the participants a broad and comparative introduction on the various delivery methods available for the different CRSPR gene-editing tools, their advantages and disadvantages.
Importantly, the workshop will try to achieve a comprehensive understanding on how to select the right delivery tool for a specific CRISPR gene editing in cells to achieve high efficacy, the so-called “CRISPR-Delivery-Cell, CDC” match-making procedure.
- Safety: Pre-Clinical Safety Analyses
- Ciaran Lee PhD (University College Cork. Ireland)
This workshop will focus on the side effects derived from the use of genome editors. The session will address the risks associated with the unspecific activity of CRISPR-based platforms, which can impact both the safety and efficacy of gene-editing approaches. Participants will gain a comprehensive understanding of the different types of potential genotoxic events and of the different methods available to monitor unintended genomic modifications, including those aligned with regulatory guidelines:
- Off-target activity of genome editors
- Genotoxicity: on- and off-target aberrations
- Off-target evaluation methods
- Mitigation strategies
- Hands-on basic training on specificity prediction
[1] GeneHumdi website: http://www.genehumdi.eu/
[2] Workshop registration: https://event.fourwaves.com/crisprmed26/registration